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          1. 當前位置:產品與服務 >坎地沙坦酯
            坎地沙坦酯

            基本信息

            化學名稱:(±)-1H-苯并咪唑-7-羧酸-2-乙氧基-1-[[2-(1H-四氮-5-基)[1,1-二苯]-4-基]甲基]-1-[[(環己基氧基)羰基]氧基]乙酯

            結構式:         
            分子式:
            C33H34N6O6
            分子量:610.67
            CAS號:145040-37-5
            質量標準:USP/ EP/ 國家標準, 可提供DMF/ CEP/ GMP。

             Specificatin

              EP 7.8

            ITEM

            CRITERIA

             RESULTES

              Appearance

               A white or almost white powder.

                White powder

              Identification-IR

              Conform to the reference spectrum

                Conforms

              Identification- UV

             Maximal absorptions at 254nm,   minimum absorption at 242nm

                Conforms

              Water

               ≤ 0.3%

                 0.19%

              Residual solvents

              Methanol

               Less than 3000ppm

                 N. D.

              Ethanol

               Less than 5000ppm

                 N. D.

              Ethyl ether

               Less than 5000ppm

                62ppm

              Acetone

               Less than 5000ppm

                505ppm

              Ethyl acetate

               Less than 5000ppm

                N. D.

              Dichloromethane

               Less than 600ppm

                N. D.

              Dimethylformamide

               Less than 880ppm

                N. D.

              Related substances

              Impurity A

               ≤ 0.15%

                0.04%

              Impurity B

               ≤ 0.3%

                0.03%

              Impurity F

               ≤ 0.2%

                0.02%

              Impurity G

                ≤ 0.2%

                0.04%

              Impurity H

                ≤ 0.15%

                N. D.

              Other individual impurity

                ≤ 0.10%

                0.04%

              Total impurities

                ≤ 0.6%

                0.23%

              Sulfated ash

                ≤ 0.1%

                0.07%

              Heavy metals

                ≤ 10ppm

                <10ppm

            Assay (Dried substance)

                99.0~101.0%

                99.9%

              Conclusion

                Conforms to EP

             
             
             
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